Last updated: March 20, 2026

San Francisco 49ers Injury Report

San Francisco 49ers injury report — 25 players currently injured. Latest injury updates, return dates, and status changes for the San Francisco 49ers (NFL).

Currently Injured (25)

• Nate Hobbs — Knee (questionable)
• Nate Hobbs — MCL (questionable)
• Jake Tonges — Foot (questionable)
• Brandon Aiyuk — Knee (out)
• Osa Odighizuwa — Elbow (questionable)
• Brandon Aiyuk — ACL (out)
• Tarron Jackson — Undisclosed (questionable)
• Mykel Williams — Undisclosed (questionable)
• Fred Warner — Undisclosed (questionable)
• Jacob Cowing — Undisclosed (questionable)
• Nick Martin — Undisclosed (questionable)
• Kurtis Rourke — Undisclosed (questionable)
• Patrick Taylor Jr. — Undisclosed (questionable)
• Trent Taylor — Undisclosed (questionable)
• Jakob Robinson — Undisclosed (questionable)
• Ji'Ayir Brown — Hamstring (questionable)
• George Kittle — Undisclosed (questionable)
• Tre Tomlinson — Undisclosed (questionable)
• Ji'Ayir Brown — Hamstring (questionable)
• Patrick Taylor Jr. — Other (questionable)
• Mykel Williams — Other (season_ending)
• Fred Warner — Other (season_ending)
• Mykel Williams — ACL (questionable)
• Fred Warner — Ankle (questionable)
• Tatum Bethune — Quad (season_ending)

Recently Returned (44)

• Nate Hobbs — Knee
• Nick Martin — Concussion
• Ben Bartch — Foot
• Mykel Williams — Knee
• Yetur Gross-Matos — Hamstring
• Marquez Valdes-Scantling — Calf
• Fred Warner — Ankle
• Nick Bosa — ACL
• Ben Bartch — Ankle
• Dre Greenlaw — Thigh
• George Kittle — Hamstring
• Patrick Taylor — Shoulder
• Tarron Jackson — Neck
• Malik Mustapha — Other
• Brandon Aiyuk — Other
• Kevin Givens — Chest
• Kurtis Rourke — Other
• Jacob Cowing — Hamstring
• Jakob Robinson — Arm
• Sam Okuayinonu — Rest

All NFL injuries